I would do a "show span" before and after on the first switch, and see what is different in the configuration.
However, I think your problem is that "spanning-tree instance 1 vlan 200" will change your MST configuration hash. You can't have difference VLAN to instance mappings in the same region: potentially you could have packets hop between different instance trees and cause a forwarding loop.
"show span mst-config" should show you.
I think "spanning-tree instance 1 vlan 200" on the third switch in the region should fix things, even if VLAN 200 doesn't actually reach it.