There are no technical concerns (AP will not overheat), but here are a few reasons it's discouranged:
- 160MHz support is "optional" for Wi-Fi Alliance certification. Your client devices may not support it.
- Since the (I)AP-335 supports 160MHz in an "80 + 80" implementation (the two 80 MHz chunks do not have to be adjacent/contiguous, the radio will drop from 4x4 to 2x2 mode when operating in this wider channel bandwidth settting. The peak datarate therefore does not increase (but if that's limited by a 2x2 client radio anyway, it will double).
- The number of 160 MHz channels (even in 80 + 80 mode) is limited. The exact number depends on your country and applicable regulatory restrictions, but you may have just two channels available in the entire band. Obviously not good in a dense enterprise deployment, but to your point it could be ok when channel reuse is not needed/critical.