It'd probably make most sense to configure them as they are likely to be deployed so you're getting a realsitic performance.
Consider channel widths for example - you could deploy 80 MHz channels to maximise throughput, but this may not be what you're going to deploy.
You will probably want to kill off low data rates & support for 802.11b on 2.4 GHz (if you're using it), and you may want to remove support for some rates on 5 GHz too (below 12Mbps?)
You should also ensure you're not using TKIP as this will force the use of legacy data rates.