That point brings up a separate question; whether a 3rd AP would be needed in that area due to the thick wall you mention.
In any event, dropping to 2x2 from 3x3 will really depend on other factors for you to evaluate. This will also only apply to laptops as most other mobiel devices are going to be 1x1 or 2x2. Some of these factors are device type (and its supported stream count), the application usage, and also the client's SNR to the AP.....if they land on 2.4GHz rather than 5.0GHz; the stream count may be irrelevant.