Yes.
Say you have a 4 members LAG involving A and B modules on VSF ( of both members)...on VSF side:
1/A1+1/B1+2/A1+2/B1 (so it spans into A and B on both VSF 1 and VSF 2)
On 3rd 5400 say you have 4 modules involved, use:
A1+B1+C1+D1
Clearly it all depends on modules availability and interfacestypes (doing so using 10G interfaces could be very expensive - you need a lot of moduled - and having a 4x10G LAG could be overkill in some scenarios). Mine is just an (extreme) example.